Are you looking to make a significant difference by contributing to drug discovery for diabetes and obesity? 
 

We are seeking a highly motivated and ambitious post-doctoral scientist to join our research team. The successful candidate will contribute to groundbreaking research aimed at significantly impacting metabolic health. The project focuses on elucidating the structure-function relationship of G protein-coupled receptor (GPCR) complexes associated with metabolic disorders, utilizing state-of-the-art structural, biochemical, and pharmacological methodologies. This position is ideal for a GPCR enthusiast eager to expand their knowledge and skills as it offers an exceptional opportunity to gain expertise in cryoEM technology for solving GPCR complex structures, while receiving mentorship from a multidisciplinary team of scientists dedicated to advancing drug discovery. We are committed to fostering a collaborative and supportive environment where you can thrive and achieve your research goals.

In this role, you will:

• Purify GPCR complexes for structural studies

• Investigate the downstream receptor signaling pathways using biochemical assays and cell-based pharmacological studies.

• Conduct structure-function studies to uncover the mechanism of receptor signaling using pharmacological tools.

• Learn and apply cryoEM technique for solving GPCR structures

• Present findings at conferences and publish in high quality peer-reviewed journals.

Basic Qualifications

• Ph.D. in Biochemistry, pharmacology, Structural Biology or biomedical-related discipline (degree must be awarded by start date).

• Hands-on experience with GPCR is strongly required.

Physical Qualifications

• Must be able to lift and move laboratory equipment or solutions weighing up to 20 pounds.
   

Additional Preferences

If you are described with these skills, you could be a great fit for the role:

• Self-directed and highly motivated individual who wants to learn new techniques while continually pursuing research and publication goals.

• Experience with GPCR purification is strongly preferred.

• Excellent communicator (oral and written) with presentation experience, along with a strong publication record.

• Candidates with previous experience in GPCR pharmacology, BRET assays, receptor signaling assays and GPCR purification are encouraged to apply

• Experience with cryo-EM is a plus.