• Job Type: Officer of Administration
• Bargaining Unit:
• Regular/Temporary: Regular
• End Date if Temporary:
• Hours Per Week: 20
• Standard Work Schedule:
• Building:
• Salary Range: $42.55-$42.55

Position Summary

The Department of Systems Biology at Columbia University Irving Medical Center is seeking to hire a part-time Bioinformatics Analyst to work in Dr. Dennis Vitkup?s lab.

The Bioinformatics Analyst will participate in analysis of large-scale genomic data in genetic studies of human conditions and diseases.

Responsibilities

• Participate in computational and statistical model development for predicting genetic effect of genomic variation.
• Participate in computational analysis of large-scale genomic data to identify risk variants and genes in human conditions and diseases, such as autism and neurodevelopmental disorders.
• Maintain and improve bioinformatics pipelines for genomic variants annotation.
• Maintenance of computational pipelines for analyzing bulk, single-cell, and spatial genomics data.
• Meet with Core users to assist with experimental design and computational analysis and the development of scientific manuscripts.
• Carry out standard/custom bioinformatics projects for Core users with standard tools for unsupervised clustering, differential expression, cell-type identification, chromatin state analysis, gene ontology/pathway enrichment, and data visualization.
• Carry out custom bioinformatics projects for Core users involving more sophisticated tools that may require adaptation to specific biological questions including inference of pseudotemporal trajectories, gene regulatory networks, and cell-cell interactions.
• Prepare computer code for reproducible analysis.
• Prepare figures and text for manuscripts and presentations.
• Develop or implement emerging computational methods for analyzing bulk and single-cell genomic data.
• Perform other duties as assigned.

Minimum Qualifications

Requires a bachelor's degree or equivalent in education and experience, plus three years of related experience

Preferred Qualifications

• Master?s degree, or higher, in biomedical informatics or systems or related field
• At least one year of experience in projects with data science or machine learning as a core component
• Proficient in Python, git, Linux-based HPC, and modern data science frameworks

Other Requirements

• Programming: Fluency with at least one general-purpose programming language (e.g. C/C++, Ruby, Perl, Python) and one language for scientific computing (R, MATLAB, Python)
• Demonstrated experience in genomic data analysis
• Demonstrated experience in statistical analysis
• Strong written and verbal communication skills

Equal Opportunity Employer / Disability / Veteran

Columbia University is committed to the hiring of qualified local residents.

About Columbia University

Columbia University is one of the world's most important centers of research and at the same time a distinctive and distinguished learning environment for undergraduates and graduate students in many scholarly and professional fields. The University recognizes the importance of its location in New York City and seeks to link its research and teaching to the vast resources of a great metropolis. It seeks to attract a diverse and international faculty and student body, to support research and teaching on global issues, and to create academic relationships with many countries and regions. It expects all areas of the university to advance knowledge and learning at the highest level and to convey the products of its efforts to the world.

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