A postdoctoral position is immediately available in the Handel laboratory at UCSD for a period of two years with the possibility of renewal.  We seek a highly motivated individual to lead the development and testing of protein therapeutics designed to reprogram the tumor microenvironment towards an antitumoral state that promotes tumor elimination. Responsibilities of the postdoc will be to design and produce the protein therapeutics, characterize their in vitro efficacy using cell-based assays, investigate their in vivo efficacy using murine models of cancer and evaluate their mechanisms of action by profiling the cell composition and inflammatory status of the tumor microenvironment pre- and post-treatment. Although the Handel lab has traditionally focused on structural and signa