Post-doctoral Research Fellow, Clinical Genetics Research Lab - Department of Medicine
Memorial Sloan Kettering Cancer Center
Location: New York, New York
Internal Number: 53224
At Memorial Sloan Kettering (MSK), we're not only changing the way we treat cancer, but also the way the world thinks about it. By working together and pushing forward with innovation and discovery, we're driving excellence and improving outcomes. We're treating cancer, one patient at a time. Join us and make a difference every day.
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Memorial Sloan Kettering Cancer Center (MSK) is one of the world's premier cancer centers, committed to exceptional patient care, leading-edge research, and superb educational programs. The blending of research with patient care is at the heart of everything we do. The institution is a comprehensive cancer center whose purposes are the treatment and control of cancer, the advancement of biomedical knowledge through laboratory and clinical research, and the training of scientists, physicians and other health care workers.
The Clinical Genetics Research Lab, Sloan Kettering Institute is seeking a highly motivated and successful individual with a background in in-vitro/in-vivo modeling of disease alleles in cancer. The successful candidate will lead NIH supported projects esearcher to conduct molecular and biochemical experiments to allow functional characterization of novel candidate genes identified through next generation sequencing and assess their role in cancer susceptibility. Applicants with a curious mindset and interest in technology/assay development are especially encouraged to apply. We are looking for a molecular biologist, preferably with a background in germline genetics and cancer biology. The goal is to merge clinical, genotypic and molecular studies to dissect complex phenotypes seen in cancers. MSKCC provides an interactive setting with opportunities for collaboration with other independent research groups.
Current projects of interest focus on the role of DNA repair gene mutations in cancer susceptibility. The applicant should have a strong interest and ideally prior experience with DNA repair pathways and relevant biochemical assays. An interest in the development of new tools to interrogate genetic variants on a larger scale would be ideal.
A PhD degree in molecular biology/cancer biology/biochemistry
Essential wet lab skills such as cell culture, molecular cloning, DNA, RNA and protein isolation, Western blotting, immunostaining etc
Extensive experience with cell culture/ in vitro assays is required, additional familiarity with animal models is an advantage
Additional desirable skills include:
Prior experience with CRISPR/Cas9 or other genome editing techniques
Familiarity with next generation sequencing approaches
Experience in developing/carrying out high throughput assays
Familiarity with genetic datasets
Please send CV, a letter outlining your interest and names/contact information of three references via email to:
Vijai Joseph PhD
Associate Attending/ Lab Director firstname.lastname@example.org
Subject: Cancer Biology PostDoc
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At Memorial Sloan Kettering (MSK), we’re not only changing the way we treat cancer, but also the way the world thinks about it. By working together and pushing forward with innovation and discovery, we’re driving excellence and improving outcomes. For the 28th year, MSK has been named a top hospital for cancer by U.S. News & World Report. We are proud to be on Becker’s Healthcare list as one of the 150 Great Places to Work in Healthcare in 2018, as well as one of Glassdoor’s Employees’ Choice Best Place to Work for 2018. We’re treating cancer, one patient at a time. Join us and make a difference every day.