Oak Ridge, Tennessee
New York, New York
Smithfield, North Carolina
Costa Mesa, California
Newark, New Jersey
Apex, North Carolina
Location: Nashville, Tennessee
Internal Number: 2200736
Research Assistant I - Genetic Medicine
Position Summary :
The Research Assistant I is part of the Division of Genetic Medicine within the Department of Medicine at Vanderbilt University Medical Center and is a key individual contributor responsible for assisting in defining developmental processes that control formation of nerves in the mouse intestine and lower urinary tract. Project work will entail but is not limited to dissection of mouse tissues, operating a cryostat for generation of tissues sections, immunohistochemistry with fluorescent microscopy to capture images of relevant cell types, and dissociation of tissues for single cell RNA-Sequencing. Project responsibilities will include working with mouse lines in a breeding colony including DNA isolation, genotyping, and timed matings. Our team members rotate through maintenance of items for laboratory operation and inventory stocking of supplies/reagents and general use buffers. Reporting directly to the Principle Investigator, the Research Assistant will interact with faculty, staff, and students within the laboratory. If you are interested in a career in medicine or biomedical research, this position is a fantastic opportunity to gain relevant skills and experience that will foster long-term success.
About the Lab:
Our lab is broadly interested in developmental processes that are essential for formation and function of peripheral nervous system ganglia that control visceral organs. We employ the mouse as a model organism and rely on transgenic models to image and isolate neural crest populations that contribute to innervation of the intestine (Musser et al., 2015; May-Zhang et al., 2021) and bladder (Wiese et al., 2017; Deal et al., 2021). We aim to define the role of specific genes in the development of neural connections by using mutant strains to understand how deficits during development predispose to altered function of organs in adult systems. We rely on approaches such as lineage tracing with Cre transgenic lines, confocal microscopy, and single cell RNA-Seq to define the regulatory networks that control when and how neural crest derivatives make cellular decisions to differentiate into one cell type versus another.
Key Functions and Expected Performance:
Conducts Wet Lab Experiments
The Division of Genetic Medicine is established to host both research and clinical research programs focused on the genetic basis of health and disease. The division provides an academic environment enabling researchers to explore new relationships between disease susceptibility and human genetics.
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Located in Nashville, Tennessee, and operating at a global crossroads of teaching, discovery and patient care, VUMC is a community of individuals who come to work each day with the simple aim of changing the world. It is a place where your expertise will be valued, your knowledge expanded and your abilities challenged. It is a place where your diversity -- of culture, thinking, learning and leading -- is sought and celebrated. It is a place where employees know they are part of something that is bigger than themselves, take exceptional pride in their work and never settle for what was good enough yesterday. Vanderbilt's mission is to advance health and wellness through preeminent programs in patient care, education, and research.
VUMC Recent Accomplishments
Because we are committed to providing the best in patient care, education and research, we are proud of our recent accomplishments:
* US News & World Report: #1 Adult Hospital in Tennessee and metropolitan Nashville, named to the Best Hospitals Honor Roll of the top 20 adult hospitals, 10 nationally ranked adult specialty programs, with 3 specialties rated in the top 10 nationally, Monroe Carell Jr. Children's Hospital at Vanderbilt named as one of the Best Children's Hospital in the nation, with 10 out of 10 pediatric specialties nationally ranked.
* Healthcare's Most Wired: Among the nation's 100 "most-wired" hospitals and health systems for its efforts in innovative medical technology.
* Becker's Hospital Review: named as one of the "100 Great Hospitals in America", in the roster of 100 Hospitals and Health Systems with Great Oncology Programs and to its list of the 100 Hospitals with Great Heart Programs.
* The Leapfrog Group: One of only 10 children's hospitals in the to be named at Leapfrog Top Hospital.
* American Association for the Advancement of Science: The School of Medicine has 112 elected fellows
* Magnet Recognition Program: Received our third consecutive Magnet designations.
* National Academy of Medicine: 22 members, elected by their peers in recognition of outstanding achievement
* Human Rights Campaign Healthcare Equality Index: 6 th year in a row that Vanderbilt University Medical Center was a Leader in LGBTQ Healthcare Equality.