JOB SUMMARY:

The Georgiev laboratory seeks qualified applicants for a Research Assistant II (RAII) role. The ideal candidate will function as a laboratory resource and make essential contributions by culturing cells (both eukaryotic & prokaryotic), performing molecular biology ( e.g. transformations, DNA preparation, PCR, sequence analysis, etc .), expressing and purifying proteins, characterizing antibodies ( e.g. ELISA), preparing common reagents, performing routine maintenance of lab equipment, inventorying reagents and supplies and carrying out other duties as necessitated. The successful candidate will under moderate supervision, set up, conduct experiments, and continue research projects following protocols including the appropriate recording of data and reporting of standard or variant results. The RAII will also assist in other laboratory and research functions. Exceptional organizational skills, verbal communication, written communication, attention to detail, and ability to function as part of a dynamic research team are required.

DEPARTMENT SUMMARY:

The Vanderbilt Vaccine Center (VVC) is recognized as one of the leading vaccine centers in the world with broad expertise in basic and clinical discovery related to understanding and optimizing disease prevention through vaccination. At the interface of immunology and virology , recent computational advances have allowed us to better understand the interactions between antibodies and antigen, to design immunogens capable of eliciting target antibody specificities, and to optimize antibodies as clinical products. Research efforts in the Georgiev laboratory aim to utilize the power of computation to increase our understanding of fundamental questions in immunology and virology and to develop novel ways of using this understanding to fight diseases. For the translational component of our research, we apply structure-based protein design approaches to the development of new vaccine and antibody product candidates against a number of viruses of biomedical interest.

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KEY RESPONSIBILITIES:

• Under moderate supervision, conduct and evaluate experiments and assays

• Display strong attention to detail

• Effectively utilize time by multi-tasking and prioritizing work assignments

• Plan, organize, and complete projects in an efficient manner

• Recognize and take charge of responsibilities

• Analyze problems and follow through to problem resolution

• Understand and follow experimental protocols (may include animal handling, tissue culture, etc.)

• Record, compile, interpret, and communicate data/results

• Follow University safety protocols (may include use of combustibles, radioactivity, toxic material, and/or carcinogens)

• Perform calculations involving molarity, % solutions, and serial dilutions

• Prepare, operate and troubleshoot equipment in experimental procedures

• Read and follow all equipment manuals

• Maintain and repair equipment according to manufacturer and University guidelines

• Ensure Laboratory is prepared for experiments

• Maintain inventories

• Maintain sterile conditions as required

• Prepare reagents

• Demonstrate an understanding of acceptable procedures and techniques

• Recognize problems and suggest solutions

• Assist in modifications as directed

• Provide appropriate written documentation of experiments

• Prepare preliminary research progress reports

• Summarize test results appropriately

TECHNICAL CAPABILITIES:

CORE ACCOUNTABILITIES:

CORE CAPABILITIES: