We are seeking motivated, innovative, skilled and enthusiastic human geneticists to join our expanding team within the Human Genetics (HG) department. Candidates should be keen to apply state of the art genetic knowledge to drive decision making across the GSK pipeline, working in partnership with scientists in HG and in the broader Research organization, to generate biological insights that will translate into innovative new medicines for patients.

At the core of GSK’s R&D approach is the identification of new medicines by leveraging the vast amounts of human genetic and genomic data now being generated and applying cutting edge technologies in functional genomics and machine learning.

Within the Human Genetics team, we leverage major scientific and technological advances, including investment in biobanks linked to large-scale human health databases, cutting-edge informatics platforms and integration of biological pathway and functional genomics data to identify novel targets. We continue to evaluate these targets throughout their life in the pipeline, using genetics and genomics to identify the patients that are most likely to benefit and biomarkers to select these patients and assess efficacy.

Successful candidates will work in a multidisciplinary, collaborative and scientifically driven environment, interacting with GSK scientists and external collaborators to advance GSK drug discovery and clinical development. This field-leading research addresses important drug discovery and development challenges, directly impacts GSK’s R&D pipeline, and leads to publication in top scientific journals. 

Key Responsibilities include, but are not limited to:

• Identify and implement opportunities for genetics-based science to improve GSK target quality and use human genetic evidence to drive decisions on target selection, validation and patient stratification.
• Be responsible for detailed genetic assessments to inform GSK project progression decisions.
• Participate and lead project teams with GSK scientists and external collaborators.
• Be responsible for effective communication of genetic findings, with expert interpretation, to relevant stakeholders and project teams.
• Find creative solutions and work with agility to address challenging scientific questions.
• Contribute to the developing science of drug target identification and validation, providing scientific expertise within Human Genetics and across the Research organization.

Multiple Locations: Collegeville, Pennsylvania; Cambridge, Massachusetts; Stevenage, United Kingdom;