The Human Target Validation Core is an innovative research unit in Translational Biology (Research & Early Development) focused on advancing the human basis of therapeutic development. Our team is building a human tissue repository, conducting single cell multi-omics profiling of preclinical models & human tissues, generating novel human genetic data from patients, and building an integrated analytics platform to derive system biological insight.
We are seeking a highly collaborative Statistical Geneticist or Genetic Epidemiologist to join a research team focused on novel target identification and validation for MS in a Research Fellow role. This newly created role at Biogen is an 18-month position designed to provide a unique opportunity for academically trained scientists to gain exposure to drug development and train in an industry research setting, while publishing scientific findings as lead authors.
The individual will be expected to lead, design and execute statistical genetic studies of MS disease severity and progression, in clinical trials and a unique collection of real-world clinical, imaging and biomarker data from MS patients in the MS PATHS cohort.
The aim is to generate novel human genetics data and integrate it with omics data for the purpose of target discovery and validation. These data will also be used to prioritize existing portfolio projects. The candidate is expected to work independently and creatively in a highly matrixed and cross-disciplinary environment, as well as foster internal and external collaborations to advance the studies. The work will involve a wide array of computational analyses using statistical genetic approaches and is expected to high quality first-author publications.