As part of its national and international scientific strategy, the Faculty of Basic and Biomedical Sciences (https://www.biomedicale.parisdescartes.fr) of the University of Paris offers to host and support awardees of the University of Paris 2019 Chair of Excellence call (https://www.biomedicale.parisdescartes.fr/chairs/). The University call will close on June 28th, 2019, at noon Paris time. The preselection procedure by the faculty will be launched on April 20th and will end on May 24th. Interviews are foreseen around mid-June. The Chair of Excellence can support either junior or senior scientists for a 3 year period (300 k€ or 500 k€, respectively). Funding can cover the salary of the awardee and/or other types of research needs depending on the current position of the applicant. If applicants do not yet hold a permanent research scientist position, the University will help awardees apply to permanent CNRS, INSERM or Faculty positions within the 3-year period.
The Faculty of Basic and Biomedical Sciences has launched an ambitious BioMedTech program covering the research projects of its constituting Research Units as well as collaborative projects. This call is part of this BioMedTech program. BioMedTech is a multidisciplinary program aiming at using the most innovative concepts and technologies to support a better understanding of biology and human pathology and to design tools to improve human health. BioMedTech integrates strong expertise in chemistry, physics, mathematics, biology, and neurobehavioral sciences. A summary of each Research Unit main projects is provided below:
INCC (Integrative Neuroscience & Cognition Center; CNRS UMR 8002) comprises 7 groups that study cognition and behaviour on several levels of observation and use various methods from optogenetics to psychophysics. We investigate (i) the result of integrative brain activity that controls cognition and behaviour, (ii) the sensorimotor and neuronal/glial basis of these integrative brain functions, and (iii) their cellular and molecular underpinnings from a neurophysiological and functional perspective (https://incc-paris.fr/).
T3S (environmental Toxicology, Therapeutic Targets, cellular Signalling and biomarkers, INSERM UMR 1124) includes 8 teams with multidisciplinary expertise aiming at identifying the major biological pathways involved in various human diseases and at delineating the effect of environment on human health, in line with the exposome concept (http://umrs1124.biomedicale.parisdescartes.fr/). Such knowledge is used to identify the cellular targets for drug development and therapeutic intervention.
SPPIN (Saints-Peres Paris Institute for Neurosciences, CNRS UMR 8003). At the SPPIN, we use a unique combination of biophysical, advanced mouse genetics, subcellular optogenetics, photochemical and advanced light-microscopic techniques in the awake animal, in vivo, along with more classical morphological, electrophysiological, and molecular biological techniques to understand brain function, with a strong, but not exclusive, focus on synaptic physiology (https://www.sppin.fr/).
MSC Med laboratory (CNRS UMR 7057) develops bioengineering, multidisciplinary and translational approaches for personalized nanomedecine, nanotoxicology, cell therapy, tissue engineering, regenerative medicine, and drug delivery (http://biother.net) as well as mechanobiology and biomechanics studies. Current projects focus on (i) the engineering of extracellular vesicles as subcellular therapy and biogenic drug delivery system, (ii) remotely-activated therapies, (iii) nanotoxicology (iv) the effects of the environment on locomotion ageing and (v) decision making in multicellular assemblies (http://www.msc.univ-paris-diderot.fr/).
LCBPT (Chemistry and Biochemistry Laboratory; CNRS UMR 8601) develops research projects at the interface between chemistry and biology. On the one side, this multidisciplinary research activity relies on the study of biological mechanisms at the molecular or supramolecular level (metabolism, chemical mediation, signaling pathways) and their involvement in physiological or pathological regulations. On the other side, it relies on the study of fundamental molecular and supramolecular reactivity and the development of molecular tools (probes, markers, sensors) to decipher biochemical mechanisms or identify/characterize/interact with new therapeutic targets. The different teams of the Unit have a recognized know-how ranging from organic and inorganic chemistry to systems biology, through bio-organic, bio-inorganic and physical chemistry (vibrational and electronic spectroscopies, NMR, EPR), pharmacochemistry, toxicology and immunology
The association of COGNAC G (Cognition and Action Group, CNRS UMR 8257) and CMLA (Centre de Mathématiques et de Leurs Applications, CNRS UMR 8536) will become the future Centre Giovanni Borelli in January 2020. Its aim is to study sensorimotor transformations in the context of human and animal behaviour. The research methodology developed within the lab consists of setting up complete pipelines for data acquisition and data processing in the field (medical consultation, hospital, flight simulator…) in order to perform modelling, quantification and qualification of behaviour in ecological conditions with cohorts of significant size (at least one order of magnitude higher than the state-of-the-art). The expertise of the Centre Borelli combines neurosciences of the sensori motor system, as well as biomedical research and applied mathematics with a focus on machine learning and complex data modelling (http://cmla.ens-paris-saclay.fr/).
The selection of candidates will be made by an independent scientific jury. Criteria are the scientific excellence of past achievements and the originality of the research project. The applicant should also show how her/his proposal can be integrated in at least one the Units projects and how it can foster increased interactions between the 6 Units.
Please send a CV, a publications list, a 2-page report on previous work, the proposed project (5 pages) as well as three reference letters.
Interviews (skype possible) and decision: mid-June 2019
Start of the program: fall 2019
Contact : Florian Waszak, firstname.lastname@example.org