The Department of Biomedical Science at the University of Central Florida is seeking applications for a Postdoctoral Research Associate in the areas of Neurodegeneration with a focus on Parkinson’s and Alzheimer’s disease. We seek highly motivated individuals who enjoy working in a team while concomitantly desiring to pursue their own ideas in a supportive environment. The lab and collaborating partners combine expertise in oxidative stress underlying the pathophysiology of Parkinson’s disease. The projects recently funded by two independent NIH R01 are aimed at (1) deciphering the roles of oxidative DNA damage in Parkinson’s disease with special emphasis on α-synuclein aggregation; (2) RNA binding proteins and its roles in subcellular localization and translational regulation of alpha synuclein mRNA with specific emphasis on mitochondrial modulation. The lab also actively works on epigenetic regulation of α-synuclein in Parkinson’s disease. For detailed description of the individual project, please see our lab website led by Dr. Yoon-Seong Kim.(https://med.ucf.edu/biomed/directory/dr-yoon-seong-kim/)
The successful applicant will have the opportunity to use an interdisciplinary approach to pursue research interests and advance to an independent research career in a supportive environment of the UCF medical city campus.
Minimum Qualifications: Ph.D. in Biomedical/Biological Science (with a focus on Neurodegeneration within the past 2 years) with background in Molecular Biology, Cell Biology, Biochemistry, Genetics or a related discipline. The ideal candidate should have a strong molecular biology background with accomplishments demonstrated by first-author publications in peer-reviewed journals.
Preferred Qualifications: Training and/or experience with genome editing technologies like CRISPR/Cas9, experience with primary neuron culture, transgenic mice line maintenance are desired. It will be advantageous to candidate, if he/she has prior experience in viral delivery of gene KD/overexpression cassettes using stereotaxic surgery in mouse and rat. Experience in recombinant protein and their characterization will be a plus. Candidates with prior working experiences in gut-brain axis in mice/rat will be preferred.