A Carnegie postdoctoral fellow position is available immediately in the Department of Plant Biology at the Carnegie Institution for Science. We are located in the heart of Stanford University’s natural sciences, medical school and engineering departments. The fellow will be co-supervised by David Ehrhardt (a leader in cell biology) and Sue Rhee (a leader in computational/systems biology) and collaborate with directors of our in-house imaging and proteomics facilities to create a plant cell atlas research program. The plant biology community lacks a comprehensive picture of where molecular machineries are located within cells and their dynamics in real time. Scientists in our department work on various aspects of the plant cell ranging from biochemical pathways, signaling pathways, transcriptional regulatory pathways, and machineries that shape cells. Yet, most of us have not explored the dynamic cellular context of the proteins we work on. For example, we do not know whether enzymes in a metabolic pathway are physically linked in a cell to provide a metabolic tunnel for efficient channeling of metabolites. Transcriptional regulators have often been observed as nuclear speckles but we do not know the composition and diversity of these subcellular structures. Likewise, proteins localize to nano and microdomains in the cell membrane and cell wall, but we do not know the composition and diversity of these domains and the functions they serve. With recent advances in molecular, imagining and proteomics technologies, and the facilities we have at hand in the Department of Plant Biology and at Stanford, we have a new opportunity to develop a dynamic cellular view of these processes that would seed the beginning of a plant cell atlas.
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Qualified candidates must have a Ph.D. or equivalent in Cell and Molecular Biology or a related field. The successful candidate should also have a demonstrated ability for independent and critical thinking, excellent communication and teamwork skills, and enthusiasm for learning new things.