Come work at NIST as a University of Maryland/NIST CNST post-doctoral fellow in microfluidic body-on-a-chip systems design, fabrication and testing! The University of Maryland/NIST Nanoscale Science and Technology Postdoctoral and Visiting Senior Fellowship Program invites applications for this position.
When new drugs are tested on patients, researchers count on animal experiments to predict the outcome. Often though, those predictions miss the mark: drugs are less effective or more toxic than assumed. That's because human metabolic pathways can differ from those in animals. The resulting metabolites can inflict unanticipated injuries in patients during clinical trials.
Microphysiologic body-on-a-chip systems provide a way to test drugs in the presence of human metabolic pathways. Those pathways are created by placing human tissues into tissue culture chambers that are interconnected via microfluidic channels (body-on-a-chip devices). We use nanofabrication and 3D-printing to create devices that can mimic the human metabolism. We test those devices with advanced tissues, and we develop on-chip biosensors that monitor tissue health on-chip.
A successful candidate will work at the NIST CNST to develop the systems described above under the mentorship of CNST Project Leader Dr. Mandy Esch and in collaboration with researchers in her laboratory.
The candidate will have an opportunity to:
Fellowships are normally awarded for two years with possibility of extension.
Candidates should have a PhD or equivalent experience in bioengineering, biomedical engineering, chemical engineering, or a related discipline.
A good publication record demonstrating original thinking, and solid background in bioengineering, particularly 3D printing, microfluidics, and/or biosensors, are a strong plus.